Press Release

Upstream Bio Announces Upsized $293 Million IPO

October 15, 2024

New York – October 15, 2024 – Cooley advised the underwriters of Upstream Bio, a clinical-stage biotech developing a monoclonal antibody to target respiratory disorders, on its upsized $293 million initial public offering (IPO). Upstream Bio offered 17,250,000 shares priced at $17 per share, which includes the full exercise of the underwriters’ option to purchase 2,250,000 additional shares. Upstream Bio’s common stock began trading on the Nasdaq Global Select Market on October 11, 2024, under the ticker symbol UPB. J.P. Morgan, TD Cowen, Piper Sandler and William Blair acted as joint book-running managers for the offering.

Partners Kristin VanderPas, David Peinsipp, Denny Won and Charlie Kim led the Cooley team that advised the underwriters.

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